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Yes. Using Python, pygame and pgs4a. The first link indicates what you need to hook, and has 50+ answers indicating various options.
https://www.quora.com/Can-I-make-an-Android-app-with-Python
https://play.google.com/store/apps/details?id=com.gmail.snigam3112.WordSudoku
Android, Pygame, PGS4A tutorial
http://shemseddine.com/oldblog/2013/11/27/pygame-android-game-pgs4a-tutorial-1/
Another one from the list (scroll down past their links) PyMob:
http://pyzia.com/apps.html