How to create a graphical interface in python

Answer 1

Take a look here:
https://www.sololearn.com/discuss/339620/?ref=app
https://www.sololearn.com/discuss/294631/?ref=app

For simple yet effective solution - use tkinter.
More advanced but a bit complex - kivy.
2D games - pygame.
2D/3D with OpenGL - pyglet.

Answer 2

I'm sure you'll ​find one of these useful. If you are not after a specific use case, you can start to play around with TkInter.

https://wiki.python.org/moin/GuiProgramming