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How to change known address value
As you know we dont have pointers in pyghon or js. So for example how we can put "10" on 0x014D memory address?
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The answer for javascript and python is simple and you already gave it yourself: we can't.
Other programs in languages that support pointers can only access memory assigned to them by the OS. Since this is a dynamic process you only use assigned addresses and operate relative to them (within bounds of assigned memory).
In embedded systems where you don't have OS it is different